| # | Children | Name | Born | Died | Father | Mother |
|---|
| 1 | | | b. 23 Oct 1766 | d. 1795 | James Matthews, Jr. | Mary Doak |
| 2 | | | b. 24 Oct 1768 | d. 20 Jul 1839 | James Matthews, Jr. | Mary Doak |
| 3 | Yes | | b. 11 Dec 1770 | d. 19 Aug 1835 | James Matthews, Jr. | Mary Doak |
| 4 | | | b. 17 Oct 1772 | d. 22 Nov 1793 | James Matthews, Jr. | Mary Doak |
| 5 | | | b. 20 Oct 1774 | d. 12 Mar 1849 | James Matthews, Jr. | Mary Doak |
| 6 | | | b. 1777 | d. Bef 1787 | James Matthews, Jr. | Mary Doak |
| 7 | | | b. 21 Nov 1792 | d. 27 Dec 1862 | James Matthews, Jr. | Mary Doak |
| 8 | Yes | | b. 13 Jan 1779 | d. 7 Jun 1847 | James Matthews, Jr. | Mary Doak |
| 9 | | | b. 27 Jun 1781 | d. Abt 1803 | James Matthews, Jr. | Mary Doak |
| 10 | | | b. 27 Dec 1782 | d. Aft 1840 | James Matthews, Jr. | Mary Doak |
| 11 | | | b. 8 Sep 1786 | d. Aft Oct 1852 | James Matthews, Jr. | Mary Doak |
| 12 | | | b. 23 Mar 1789 | d. 1789 | James Matthews, Jr. | Mary Doak |
1749 - 1833 (83 years)